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قديم(ـة) 05-16-2014, 05:16 PM
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XRumerTest will become famous soon enough

Inho Jo1 and H William Harris Jr1Correspondence: H William Harris Jr MD PhD, Division of Nephrology, Room 1260, John Enders Research Laboratory, Children's Hospital, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.
Top of pageAbstractClassic laboratory studies performed in the 1950's and 1960's focused on the structures and biochemical actions of multiple neurohypophysial peptides that possessed profound effects on the overall water balance of many vertebrates [reviewed in 1]. These data emphasized the importance of antidiuretic hormones (ADH) in the evolution of vertebrates and provided a framework for our current understanding of their roles in renal function. In a similar fashion, the recent discovery of the family of aquaporin water channel proteins has supplied new tools to examine the molecular aspects of ADH elicited water transport in epithelial physiology. Data concerning the structure and distribution of aquaporin water channels have been further advanced by recent research defining several of the most basic aspects of hormonally regulated transport in many cell types. Together, these findings have provided many new insights into the apical membrane events set in motion by the binding of ADH to the basolateral membrane of epithelial cells.
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